R&D headquarters and the largest tech campus in Ann Arbor. Focuses on autonomous driving, AI, and next-generation vehicle technology for the North American market.

Google's largest Midwest engineering hub, housing Cloud, Ads, and product teams. Operating in Ann Arbor since 2006.

Founded downtown as Duo Security and acquired by Cisco for $2.35B. The definitive Ann Arbor tech success story and the origin of modern push-based multi-factor authentication.

Advanced semiconductor inspection and metrology systems. Anchor tenant of the Research Park Drive corridor and a major node in the global chip inspection supply chain.

Multiple Amazon operations in the Ann Arbor area, including engineering, applied science, advertising, and logistics teams contributing to Amazon's global platform.

Microsoft engineering office contributing to cloud, enterprise collaboration, and developer platform products. Part of the Traverwood-adjacent tech corridor.

U-M robotics spinout deploying autonomous shuttles in real cities. $300M+ raised from Toyota, Bridgestone, BMW i Ventures, and State Farm. Ann Arbor HQ.

U-M research spinout running a continuous global scan of the public internet. Provides attack surface management and internet intelligence to enterprise and government customers. $100M+ raised.

Longstanding Ann Arbor information services company. Acquired by Clarivate in 2021 for $5.3B. Operates the scholarly and academic data infrastructure used by universities and libraries worldwide.

Ann Arbor's largest employer and top-ten engineering school. Runs a $1.8B annual research budget and operates Mcity, the world's first purpose-built connected-vehicle testbed. The city's tech talent engine.

Autonomous vehicle simulation and infrastructure software used by most major automakers and several defense primes. $1B+ raised. Dual Mountain View and Ann Arbor operations.

Healthcare AI platform that optimizes hospital operations, infusion centers, and operating rooms. Used by 180+ health systems. Growing Ann Arbor engineering hub.

Conversational AI platform for financial services. U-M Clarity Lab spinout. $70M+ raised from Drive Capital, Baidu Ventures, and others.

Virtual-first substance use disorder treatment platform combining medication-assisted treatment, therapy, and coaching. $118M+ raised. Operating in most US states.

Employee-owned custom software consultancy. Ann Arbor and Grand Rapids offices. Consistently recognized on Best Places to Work lists. Deep TDD and pair programming practice.

Bootstrapped CRM and sales automation platform serving B2B sales teams since 2009. Profitable, opinionated, and the clearest example of durable SaaS built in Ann Arbor.

Vertical SaaS for service businesses: salons, pet groomers, tattoo studios, veterinary clinics. 200+ employees. Ann Arbor-based since 2001.

Legal technology and information services employer with significant Ann Arbor engineering presence contributing to AI-powered legal research products.

Top-tier Microsoft Azure Partner (now operating as intlx Solutions). Delivers cloud migration, managed services, and zero-trust security programs for enterprise clients.

Autonomous robotic delivery startup founded by U-M faculty. The REV-1 robots have been delivering groceries and meals in Ann Arbor for years, logging real-world autonomy miles that few peers can match.

The origin story of Ann Arbor cybersecurity. U-M spinout that invented modern DDoS detection and mitigation. Acquired by NETSCOUT in 2015 and still operating from Ann Arbor as a core piece of NETSCOUT's security business.

Supply chain design and analytics software acquired by Coupa in 2020 for $1.5B. Now the core of Coupa Supply Chain Design and Planning. One of the largest enterprise software exits in Michigan history.

Custom software consultancy famous for 100% pair programming and the 'Joy, Inc.' operating model. Hosts tours and training for teams worldwide. Downtown Ann Arbor since 2001.

Autonomous vehicle simulation and real-time robotics software. Acquired by Ford in 2020 and now a core part of Ford's self-driving and ADAS effort. Based in Saline, minutes south of Ann Arbor.

Healthcare data analytics for clinical registries, medical societies, and health systems. Powers national quality measurement programs in cardiology, orthopedics, and other specialties.

Computer vision ML platform company and creator of FiftyOne, the open-source dataset and model evaluation toolkit used across the global ML community. U-M spinout with $50M+ raised.

Publicly traded AI-powered learning platform (Nasdaq: AMST). Founded by former U-M engineering professor Ann Marie Sastry. Generative AI for enterprise knowledge and training.

Detection and response platform for small and mid-sized businesses. Founded by former Duo Security engineers. $30M+ raised from M12 and Mercury. One of the clearest examples of A2 security alumni building the next generation.

Semiconductor IP company building intelligent clock network technology for AI accelerators, high-performance compute, and automotive silicon. $30M+ raised from Bosch Ventures and TDK Ventures.

Publicly traded biotech (Nasdaq: ESPR) developing cardiovascular therapies. FDA-approved drugs Nexletol and Nexlizet reduce LDL cholesterol in statin-intolerant patients. CLEAR Outcomes trial validated CV event reduction in 2023.

Adobe Commerce and Magento development shop serving retailers, consumer brands, and B2B manufacturers nationwide. One of the most respected ecommerce agencies in the Midwest.

Enterprise software consultancy built on 100% onshore delivery. Acquired by NTT DATA in 2021. Serves Fortune 500 clients in retail, financial services, healthcare, and logistics.

Ann Arbor engineering site for Barracuda's global email protection, network security, and application security products. Deployed in hundreds of thousands of organizations worldwide.

Media and entertainment IP licensing company spun out of Xperi in 2022. Patent portfolio spans semiconductor packaging, content delivery, and media experience technologies. Ann Arbor R&D presence.

Industrial software consultancy acquired by Accenture in 2018 and now operating as part of Accenture Industry X. Specializes in connected products and modern software practices for manufacturers and automakers.

Network analytics platform for ISPs, content providers, and cloud operators. Acquired by Nokia in 2017 and continues to operate from Ann Arbor as a core piece of Nokia's IP Networks portfolio.

Machine learning platform that turns unstructured commercial insurance documents into clean structured data. Used by major commercial carriers and broker organizations for underwriting and analytics.

Biotech tools company using buoyancy-based microbubbles (BACS) to separate cells faster and more gently than traditional methods. U-M spinout being adopted across research and cell therapy manufacturing.

Genomic intelligence platform applying machine learning to the entire scientific literature to curate gene-variant-disease evidence. Used by clinical labs for variant interpretation and by pharma for drug discovery.

TomTom's North American automotive office contributing to in-vehicle navigation software, HD maps, and automotive-grade location services shipping in millions of vehicles.